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NEK9 Mouse anti-Human, Clone: OTI1H1, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA503326

Encompass_Preferred

Catalog No. 50-167-4253


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Description

Description

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.
Specifications

Specifications

NEK9
Monoclonal
0.45 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q8TD19
NEK9
Full length human recombit protein of human NEK9 produced in HEK293 cell.
100 μL
Primary
Human
Antibody
IgG1
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1H1
Unconjugated
NEK9
APUG, LCCS10, NC, NERCC, NERCC1
Mouse
Affinity Chromatography
RUO
91754
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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