NEK9 Mouse anti-Human, Clone: OTI1H1, liquid, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene TA503326

Catalog No. 50-167-4253

Description

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.

Specifications

• Antigen: NEK9
• Classification: Monoclonal
• Concentration: 0.45 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8TD19
• Gene Alias: APUG, LCCS10, NC, NERCC, NERCC1
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 91754

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1H1
• Conjugate: Unconjugated
• Gene: NEK9
• Format: Liquid
• Gene Symbols: NEK9
• Immunogen: Full length human recombit protein of human NEK9 produced in HEK293 cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human