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Invitrogen™ NEK9 Polyclonal Antibody
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Catalog No. PIPA533963
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50 μg
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PIPA533963 50 μg
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Catalog No. PIPA533963 Supplier Invitrogen™ Supplier No. PA533963
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%); Mouse, Rat, Dog, Bovine, Bat, Opossum (93%); Platypus (87%); Turkey, Chicken (80%). Proteinase K treatment is required for antigen retrieval.

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NEK9
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene NEK9
Gene Accession No. Q8TD19
Gene Alias APUG; C130021H08Rik; DKFZp434D0935; KIAA1995; LCCS10; MGC138306; MGC16714; NC; NEK 9; NEK8; NEK9; Nercc; Nercc 1 kinase; NERCC1; Nercc1 kinase; never in mitosis A-related kinase 9; NIMA (never in mitosis gene a)- related kinase 9; NIMA (never in mitosis gene a)-related expressed kinase 9; NIMA related kinase 9; NimA-related kinase 8; NIMA-related kinase 9; nimA-related protein kinase 9; Serine/threonine-protein kinase Nek9
Gene Symbols NEK9
Host Species Rabbit
Immunogen Synthetic 15 amino acid peptide from Pro/Ser/Thr rich domain of human NEK9.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100057328, 100152772, 100338595, 100759330, 91754
Target Species Human, Rabbit, Monkey, Hamster, Pig, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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