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Invitrogen™ NEK9 Polyclonal Antibody
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Catalog No. PIPA5115636
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PIPA5115636 100 μL
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Catalog No. PIPA5115636 Supplier Invitrogen™ Supplier No. PA5115636
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Nek9.

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NEK9
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene NEK9
Gene Accession No. Q8K1R7, Q8TD19
Gene Alias APUG; C130021H08Rik; DKFZp434D0935; KIAA1995; LCCS10; MGC138306; MGC16714; NC; NEK 9; NEK8; NEK9; Nercc; Nercc 1 kinase; NERCC1; Nercc1 kinase; never in mitosis A-related kinase 9; NIMA (never in mitosis gene a)- related kinase 9; NIMA (never in mitosis gene a)-related expressed kinase 9; NIMA related kinase 9; NimA-related kinase 8; NIMA-related kinase 9; nimA-related protein kinase 9; Serine/threonine-protein kinase Nek9
Gene Symbols NEK9
Host Species Rabbit
Immunogen A synthesized peptide derived from human NEK9(Accession Q8TD19), corresponding to amino acid residues S750-N800.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 217718, 91754
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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