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Invitrogen™ NELF Polyclonal Antibody
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Catalog No. PIPA542179
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100 μL
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PIPA542179 100 μL
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Catalog No. PIPA542179 Supplier Invitrogen™ Supplier No. PA542179
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Description

Rabbit Polyclonal Antibody

Peptide sequence: GAAASRRRAL RSEAMSSVAA KVRAARAFGE YLSQSHPENR NGADHLLADA Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rat: 100%.

NELF (nasal embryonic luteinizing hormone-releasing hormone factor) is a 530 amino acid transcription factor involved in the migration of LHRH neurons, outgrowth of olfactory axons and suppression of transcription elongation. NELF is found in the peripheral and central nervous system during embryonic development, and is highly expressed in adult testis, kidney and brain. Known to couple NMDA receptor signaling to the nucleus, NELF knockdown impaired GnRH neuronal migration of NLT cells in vitro and the gene encoding NELF has been linked to the development of Idiopathic hypogonadotropic hypogonadism (IHH), a disorder resulting in impaired pubertal maturation and reproductive function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NELF
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene NSMF
Gene Accession No. Q6X4W1
Gene Alias HH9; Jac; Jacob; Jacob protein; Juxtasynaptic attractor of caldendrin on dendritic boutons protein; nasal embryonic LHRH factor; Nasal embryonic luteinizing hormone-releasing hormone factor; NELF; NMDA receptor synaptonuclear signaling and neuronal migration factor; NSMF
Gene Symbols NSMF
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human NELF (aa 2-51).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26012
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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