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Invitrogen™ NELF Polyclonal Antibody
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Catalog No. PIPA560674
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100 μL
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Catalog No. Quantity
PIPA560674 100 μL
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Catalog No. PIPA560674 Supplier Invitrogen™ Supplier No. PA560674
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KLNVYHKGAK IWKMLIFCQG GPGHLYLLKN KVATFAKVEK EEDMIHFWKR LSRLMSKVNP EPNVIHIMGC YILGNPNGEK LFQNLRTLMT PYRVTFESPL ELSAQGKQMI ETYFDFRL Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

NELF (nasal embryonic luteinizing hormone-releasing hormone factor) is a 530 amino acid transcription factor involved in the migration of LHRH neurons, outgrowth of olfactory axons and suppression of transcription elongation. NELF is found in the peripheral and central nervous system during embryonic development, and is highly expressed in adult testis, kidney and brain. Known to couple NMDA receptor signaling to the nucleus, NELF knockdown impaired GnRH neuronal migration of NLT cells in vitro and the gene encoding NELF has been linked to the development of Idiopathic hypogonadotropic hypogonadism (IHH), a disorder resulting in impaired pubertal maturation and reproductive function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NELF
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NSMF
Gene Accession No. Q6X4W1
Gene Alias HH9; Jac; Jacob; Jacob protein; Juxtasynaptic attractor of caldendrin on dendritic boutons protein; nasal embryonic LHRH factor; Nasal embryonic luteinizing hormone-releasing hormone factor; NELF; NMDA receptor synaptonuclear signaling and neuronal migration factor; NSMF
Gene Symbols NSMF
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NSMF. Recombinant protein control fragment (Product #RP-93053).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26012
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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