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NELFA Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572001
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50-157-2001 100 μL
50-157-2002 10 μL
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Catalog No. 50-157-2001 Supplier Bethyl Laboratories, Inc Supplier No. IHC00383
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Guinea pig_10141, Orangutan, Monkey, Gorilla, Chimpanzee, hirteen-lined ground

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

Specifications

Antigen NELFA
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene NELFA
Gene Accession No. Q9H3P2
Gene Alias FLJ10442, FLJ25112, NELF-A, NELFA, P/OKcl.15
Gene Symbols NELFA
Host Species Rabbit
Immunogen Between 499 and 549
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7469
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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