Nepsilon-Boc-Nalpha-Fmoc-L-lysine, 98%

Description

CAS: 71989-26-9 | C26H32N2O6 | 468.55 g/mol

It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.

Solubility
Slightly soluble in water.

Notes
Refrigerate. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 71989-26-9
• Molecular Formula: C26H32N2O6
• Molecular Weight (g/mol): 468.55
• MDL Number: MFCD000371
• InChI Key: UMRUUWFGLGNQLI-ANBDAQEENA-N
• Synonym: fmoc-lys boc-oh, fmoc-lys boc, na-fmoc-ne-boc-l-lysine, n-alpha-fmoc-nepsilon-boc-l-lysine, nepsilon-boc-nalpha-fmoc-l-lysine, nepsilon-tert-butoxycarbonyl-nalpha-9h-fluoren-9-ylmethoxy carbonyl-l-lysine, n-fmoc-n'-boc-l-lysine, n-alpha-fmoc-n-epsilon-tert-boc-l-lysine, n, a-fmoc-n, a-boc-l-lysine, s-2-9h-fluoren-9-yl methoxy carbonyl amino-6-tert-butoxycarbonyl amino hexanoic acid
• PubChem CID: 2724628
• IUPAC Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
• SMILES: CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)C(O)=O

• Melting Point: 130°C to 135°C
• Quantity: 5 g
• Beilstein: 4217767
• Solubility Information: Slightly soluble in water.
• Optical Rotation: −12° (c=1 in DMF)
• Formula Weight: 468.54
• Percent Purity: 98%
• Chemical Name or Material: Nepsilon-Boc-Nalpha-Fmoc-L-lysine

Safety and Handling

EINECSNumber	276-256-4
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only