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NES Monoclonal Antibody (OTI3B12), TrueMAB™, OriGene
SDP

Catalog No. 501682619
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100 μL
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Catalog No. Quantity
50-168-2619 100 μL
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Catalog No. 50-168-2619 Supplier OriGene Supplier No. TA809183
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Description

Mouse Monoclonal Antibody

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predomit marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

Specifications

Antigen NES
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3B12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene NES
Gene Accession No. P48681
Gene Alias Nbla00170
Gene Symbols NES
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 99-349 of human NES produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10763
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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