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Invitrogen™ Nestin Monoclonal Antibody (1A9G12)
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Catalog No. PIMA517136
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100 μg
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Catalog No. Quantity
PIMA517136 100 μg
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Catalog No. PIMA517136 Supplier Invitrogen™ Supplier No. MA517136
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Description

Mouse Monoclonal Antibody

MA5-17136 targets NES in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17136 immunogen is purified recombinant fragment of human NES (amino acids: 419-588 ) expressed in E. Coli. MA5-17136 detects NES which has a predicted molecular weight of approximately 177kDa.

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nestin
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 1A9G12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Nes
Gene Accession No. P48681
Gene Alias AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin
Gene Symbols Nes
Host Species Mouse
Immunogen Purified recombinant fragment of human NES (amino acids: 419-588 ) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10763
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM
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