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Invitrogen™ Nestin Monoclonal Antibody (2C1.3A11)
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Catalog No. 01674941
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100 μL
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Catalog No. Quantity
01-674-941 100 μL
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Catalog No. 01-674-941 Supplier Invitrogen™ Supplier No. MA15840
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Description

Mouse Monoclonal Antibody

MA1-5840 detects Nestin in human samples, and does not cross-react with rodent. MA1-5840 has been successfully used in immunohistochemistry and Western blot procedures. The MA1-5840 immunogen is 150-amino-acid fragment from the cloned human nestin conjugated to GST.

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nestin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2C1.3A11
Concentration 1.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Nes
Gene Accession No. P48681
Gene Alias AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin
Gene Symbols Nes
Host Species Mouse
Immunogen A 150-amino-acid fragment from the cloned human nestin conjugated to GST.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10763
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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