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Invitrogen™ Nestin Monoclonal Antibody (3k1)
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Catalog No. PIMA126777
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50 μg
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Catalog No. Quantity
PIMA126777 50 μg
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Catalog No. PIMA126777 Supplier Invitrogen™ Supplier No. MA126777
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Description

Mouse Monoclonal Antibody

Recommended positive controls: Human neural progenitors and A172 cells. MA1-26777 will not react with rodent. Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot- add 50% glycerol and store at -20°C or below. Avoid freeze-thaw cycles.

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Nestin
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3k1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and no preservative; pH 7.4
Gene Nes
Gene Accession No. P48681, Q6P5H2
Gene Alias AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin
Gene Symbols Nes
Host Species Mouse
Immunogen NS0 cells transfected with human Nestin.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10763, 18008
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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