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Invitrogen™ NEU1 Polyclonal Antibody
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Catalog No. PIPA554430
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100 μL
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PIPA554430 100 μL
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Catalog No. PIPA554430 Supplier Invitrogen™ Supplier No. PA554430
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RDGVFCLLSD DHGASWRYGS GVSGIPYGQP KQENDFNPDE CQPYELPDGS VVINARNQNN YHCHCRIVLR SYDACDTLRP RDVTFDPELV DPVVAAGAVV TSSGIVFFSN PAHPEFRVNL TLRWSFSNG Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NEU1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NEU1
Gene Accession No. Q99519
Gene Alias AA407268; AA407316; Acetylneuraminyl hydrolase; Aglp; Apl; Bat7; Bat-7; EC 3.2.1.18; exo-alpha-sialidase; FLJ93471; G9; G9 sialidase; HLA-B-associated transcript 7; lysosomal sialidase; Map-2; N-acetyl-alpha-neuraminidase 1; NANH; Neu; NEU1; Neu-1; neuraminidase 1; neuraminidase 1 (lysosomal sialidase); SIAL1; sialidase 1; sialidase 1 (lysosomal sialidase); sialidase-1
Gene Symbols NEU1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NEU1. Recombinant protein control fragment (Product #RP-90541).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4758
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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