Invitrogen™ Neurensin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543451

Catalog No. PIPA543451

Description

Peptide sequence: LLLLLGVAAL TTGYAVPPKL EGIGEGEFLV LDQRAADYNQ ALGTCRLAGT Sequence homology: Cow: 86%; Dog: 100%; Guinea Pig: 83%; Horse: 93%; Human: 100%; Pig: 92%; Rabbit: 100%.

Neurensin-2 (NRSN2) is a 204 amino acid multi-pass membrane protein belonging to the VMP family that may be involved in the transport and maintenance of vesicles. Expressed in brain, Neurensin-2 localizes to cell bodies of hippocampus, diagonal band, amygdaloid nucleus, and habenula nucleus, and is a potential tumor suppressor gene and candidate biomarker for long-term survival in patients with hepatocellular carcinoma (HCC). The gene encoding Neurensin-2 maps to human chromosome 20, which comprises approximately 2% of the human genome, contains nearly 63 million bases and encodes over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Specifications

• Antigen: Neurensin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRSN2
• Gene Alias: C20orf98; dJ1103G7.6; FLJ23329; Gm123; neurensin 2; Neurensin2; Neurensin-2; NRSN2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80023
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9GZP1
• Gene Symbols: NRSN2
• Immunogen: Synthetic peptide directed towards the middle region of human NRSN2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov