Invitrogen™ Neurensin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537188

Catalog No. PIPA537188

Description

This antibody detects endogenous protein at a molecular weight of 22 kDa. Purity is >95% by SDS-PAGE.

Neurensin-2 (NRSN2) is a 204 amino acid multi-pass membrane protein belonging to the VMP family that may be involved in the transport and maintenance of vesicles. Expressed in brain, Neurensin-2 localizes to cell bodies of hippocampus, diagonal band, amygdaloid nucleus, and habenula nucleus, and is a potential tumor suppressor gene and candidate biomarker for long-term survival in patients with hepatocellular carcinoma (HCC). The gene encoding Neurensin-2 maps to human chromosome 20, which comprises approximately 2% of the human genome, contains nearly 63 million bases and encodes over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Specifications

• Antigen: Neurensin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRSN2
• Gene Alias: C20orf98; dJ1103G7.6; FLJ23329; Gm123; neurensin 2; Neurensin2; Neurensin-2; NRSN2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 228777, 689978, 80023
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide
• Gene Accession No.: Q5HZK2, Q9GZP1
• Gene Symbols: NRSN2
• Immunogen: A synthetic peptide corresponding to residues in human Neurensin-2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG