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NeuroD1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983532
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Catalog No. Quantity
50-198-3532 100 μL
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Catalog No. 50-198-3532 Supplier Bioss Supplier No. BS1517R
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Description

Rabbit Polyclonal Antibody

NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

Specifications

Antigen NeuroD1
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NEUROD1
Gene Accession No. Q13562
Gene Alias Basic helix-loop-helix factor 1; basic helix-loop-helix transcription factor; Beta2; beta-cell E-box transactivator 2; Beta-cell E-box transcriptional activator 2; BHF1; BHF-1; BHLHA3; Class A basic helix-loop-helix protein 3; MODY6; NEUROD; NEUROD1; neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD; neuronal differentiation 1
Gene Symbols NEUROD1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NeuroD1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4760
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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