Invitrogen™ NeuroD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104530

Catalog No. PIPA5104530

Description

Antibody detects endogenous levels of total NDF2.

Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.

Specifications

• Antigen: NeuroD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NEUROD2
• Gene Alias: BHLHA1; Brain bHLH protein KW8; class A basic helix-loop-helix protein 1; NDF2; NDR2; NDRF; NeuroD2; neuroD-related factor; neurogenic basic-helix-loop-helix protein; neurogenic differentiation 2; neurogenic differentiation factor 2; neuronal differentiation 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18013, 4761, 54276
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q15784, Q62414, Q63689
• Gene Symbols: NEUROD2
• Immunogen: A synthesized peptide derived from human NEUROD2(Accession Q15784), corresponding to amino acid residues K74-Q124.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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