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Invitrogen™ Neurofascin Polyclonal Antibody
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Catalog No. PIPA5102681
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100 μL
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Catalog No. Quantity
PIPA5102681 100 μL
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Catalog No. PIPA5102681 Supplier Invitrogen™ Supplier No. PA5102681
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NFASC.

Neurofascin encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. Neurofascin undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Neurofascin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NFASC
Gene Accession No. O94856, P97685, Q810U3
Gene Alias AA387016; D430023G06Rik; DKFZp686P2250; KIAA0756; KIAA0756FLJ46866; mKIAA0756; neurofascin; neurofascin homolog; NF; Nfasc; NRCAML
Gene Symbols NFASC
Host Species Rabbit
Immunogen A synthesized peptide derived from human NFASC(Accession O94856), corresponding to amino acid residues G1313-A1347.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116690, 23114, 269116
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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