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Invitrogen™ Neurofascin Polyclonal Antibody
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Catalog No. PIPA5142767
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100 μg
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Catalog No. Quantity
PIPA5142767 100 μg
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Catalog No. PIPA5142767 Supplier Invitrogen™ Supplier No. PA5142767
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize reported isoforms 1, 2, 3 and 4 (NP_001005388.2;,NP_001153803.1, NP_001153804.1and NP_055905.2 resp). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Neurofascin encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. Neurofascin undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Neurofascin
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene NFASC
Gene Accession No. O94856
Gene Alias AA387016; D430023G06Rik; DKFZp686P2250; KIAA0756; KIAA0756FLJ46866; mKIAA0756; neurofascin; neurofascin homolog; NF; Nfasc; NRCAML
Gene Symbols NFASC
Host Species Goat
Immunogen Peptide with sequence C-NFSPNQTKFTVQRT.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23114
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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