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Invitrogen™ Neurofascin Polyclonal Antibody
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Catalog No. PIPA578668
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100 μL
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Catalog No. Quantity
PIPA578668 100 μL
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Catalog No. PIPA578668 Supplier Invitrogen™ Supplier No. PA578668
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Description

Rabbit Polyclonal Antibody

Positive Control: mouse brain, rat brain Predicted Reactivity: Human (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Neurofascin encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. Neurofascin undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Neurofascin
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene NFASC
Gene Accession No. P97685, Q810U3
Gene Alias AA387016; D430023G06Rik; DKFZp686P2250; KIAA0756; KIAA0756FLJ46866; mKIAA0756; neurofascin; neurofascin homolog; NF; Nfasc; NRCAML
Gene Symbols NFASC
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Intracellular domain of mouse Neurofascin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116690, 269116
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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