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Neurofascin Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980205
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Catalog No. Quantity
50-198-0205 100 μL
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Catalog No. 50-198-0205 Supplier Bioss Supplier No. BS0289R
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Description

Rabbit Polyclonal Antibody

Neurofascin encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. Neurofascin undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.

Specifications

Antigen Neurofascin
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NFASC
Gene Accession No. O94856
Gene Alias AA387016; D430023G06Rik; DKFZp686P2250; KIAA0756; KIAA0756FLJ46866; mKIAA0756; Neurofascin; neurofascin homolog; NF; Nfasc; NRCAML
Gene Symbols NFASC
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Neurofascin-155.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23114
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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