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NEUROG1 Mouse anti-Human, Clone: 1E1H6, Proteintech
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Catalog No. 501737060 Shop All Proteintech Group Inc Products
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50-173-7060 150 μL
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Catalog No. 50-173-7060 Supplier Proteintech Group Inc Supplier No. 666421IG150UL
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Mouse Monoclonal Antibody

Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.

Specifications

Antigen NEUROG1
Applications Western Blot
Classification Monoclonal
Clone 1E1H6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene NEUROG1
Gene Accession No. Q92886
Gene Alias AKA, bHLHa6, Math4C, NEUROD3, NEUROG1, neurogenin 1, NGN, NGN 1, ngn1
Gene Symbols NEUROG1
Host Species Mouse
Immunogen NEUROG1 Fusion Protein Ag26438
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4762
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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