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NEUROG1 Mouse anti-Human, Clone: OTI5H10, liquid, TrueMAB™
SDP

Catalog No. 501671455
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50-167-1455 100 μL
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Catalog No. 50-167-1455 Supplier OriGene Supplier No. TA500304
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Description

Mouse Monoclonal Antibody

Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.

Specifications

Antigen NEUROG1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone OTI5H10
Concentration 0.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene NEUROG1
Gene Accession No. Q92886
Gene Alias AKA, Math4C, NEUROD3, bHLHa6, ngn1
Gene Symbols NEUROG1
Host Species Mouse
Immunogen Full-length protein expressed in 293T cell transfected with human NEUROG1 expression vector
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4762
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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