Invitrogen™ Neurogenin 1 Monoclonal Antibody (OTI9A8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524901

Catalog No. PIMA524901

Description

Neurogenin 1 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), IP

Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.

Specifications

• Antigen: Neurogenin 1
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q92886
• Gene Symbols: NEUROG1
• Immunogen: Full length human recombinant protein of NEUROG1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: OTI9A8
• Conjugate: Unconjugated
• Gene: NEUROG1
• Gene Alias: AKA; ATH4C; basic helix-loop-helix transcription factor; bHLHa6; cb260; chunp6899; class A basic helix-loop-helix protein 6; Helix-loop-helix protein mATH-4C; Math4C; Neurod3; NEUROG1; Neurogenic basic-helix-loop-helix protein; neurogenic differentiation 3; neurogenic differentiation factor 3; neurogenin; neurogenin 1; neurogenin related protein-1; neurogenin-1; Neurogenin-related protein 1; NGN; Ngn1; NGN-1; ngr1; transcription factor; Zath4c; zNgn1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4762
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid