Invitrogen™ Neurogranin Monoclonal Antibody (C2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA541648

Catalog No. PIMA541648

Description

Neurogranin Monoclonal Antibody for Western Blot, IHC (P)

Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

Specifications

• Antigen: Neurogranin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q92686
• Gene Symbols: NRGN
• Immunogen: Recombinant protein Neurogranin. The antigen corresponds to amino acid range 1-67 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Clone: C2
• Conjugate: Unconjugated
• Gene: NRGN
• Gene Alias: 0710001B06Rik; AI838505; B-50 immunoreactive C-kinase substrate; BICKS; calmodulin-binding protein; hng; NEUG(55-78); Neurogranin; neurogranin (protein kinase C substrate, RC3); ng; NG/RC3; NRGN; p17; postsynaptic spine 1; protein kinase C substrate; protein kinase C substrate 7.5 kDa protein; protein kinase C substrate, RC3; Pss1; R75334; RC3; similar to neurogranin
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 4900
• Content And Storage: -20°C
• Form: Liquid