Invitrogen™ Neuropeptide B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120468

Catalog No. PIPA5120468

Description

Positive test controls include: SW480, Mouse brain. The target is usually found in the following locations: Secreted. Immunogen sequence: MARSATLAAA ALALCLLLAP PGLAWYKPAA GHSSYSVGRA AGLLSGLRRS PYARRSQPYR GAEPPGGAGA SPELQLHPRL RSLAVCVQDV APNLQRCERL PDGRGTYQCK ANVFLSLRAA DCLAA.

Neuropeptide B is a endrogenous ligand of the orphan G protein coupled receptor GPR7. NPB and GPR7 exist in close proximity in the rat hypothalamus, and are ideally positioned to modulate neuroendocrine functions. NPB-immunoreactivity was enriched in many regions within the hypothalamus which also contained high levels of GPR7 mRNA including the ventrormedial hypothalamic nucleus, dorsomedial hypothalamic nucleus, arcuate nucleus, supraoptic retrochiasmatic nucleus, and in the area ventral to the zona incerta.

Specifications

• Antigen: Neuropeptide B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPB
• Gene Alias: hPPL7; L7; L7C; mPPL7; neuropeptide B; Neuropeptide B-23; Neuropeptide B-29; NPB; NPB23; NPB29; PPL7; PPNPB; preproneuropeptide B; prepro-NPB; preproprotein L7; rPPL7
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 208990, 256933
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.78 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8K4P1, Q8NG41
• Gene Symbols: NPB
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human NPB (NP_683694.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG