Invitrogen™ Neuropilin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588742

Catalog No. PIPA588742

Description

Immunogen sequence: GLIADSQISA SSTQEYLWSP SAARLVSSRS GWFPRIPQAQ PGEEWLQVDL GTPKTVKGVI IQGARGGDSI TAVEARAFVR KFKVSYSLNG KDWEYIQDPR TQQPKLFEGN MHYDTPDIRR FDPIPAQYVR VYPERWSPAG IGMRLEVLGC DWTDSKPTVE TLGPTVKSEE TTTPYPTEEE ATECGENCSF EDDKDLQLPS GFNCNFDFLE EPCGWMYDHA KWLRTTWASS SSPNDRTFPD DRNFLRLQSD SQREGQYARL ISPPVHLPRS PVCMEFQYQA TGGRGVALQV VREASQES; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Membrane, Single-pass type I membrane protein.

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: Neuropilin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRP2
• Gene Alias: 1110048P06Rik; neuropilin 2; neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); Np2; Np-2; Npn2; Npn-2; NRP2; PRO2714; receptor for VEGF165 and semaphorins class3; vascular endothelial cell growth factor 165 receptor 2; VEGF165R2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18187, 81527
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.12 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O35276, O35375
• Gene Symbols: NRP2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 443-740 of human NRP2 (NP_0038632).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG