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Invitrogen™ Neuroserpin Polyclonal Antibody
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Catalog No. PIPA5110636
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100 μL
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PIPA5110636 100 μL
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Catalog No. PIPA5110636 Supplier Invitrogen™ Supplier No. PA5110636
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DESEVQIPMM YQQGEFYYGE FSDGSNEAGG IYQVLEIPYE GDEISMMLVL SRQEVPLATL EPLVKAQLVE EWANSVKKQK VEVYLPRFTV EQEIDLKDVL KALGI Highest antigen sequence indentity to the following orthologs: Mouse - 95%, Rat - 95%.

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Neuroserpin
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Serpini1
Gene Accession No. Q99574
Gene Alias AI837402; DKFZp781N13156; neuroserpin; Ns; Peptidase inhibitor 12; PI12; PI-12; protease inhibitor 17; raPIT5a; serine (or cysteine) peptidase inhibitor, clade I, member 1; serine (or cysteine) proteinase inhibitor clade member 1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serine protease inhibitor 17; serpin family I member 1; serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; serpin peptidase inhibitor, clade I, member 1; SERPINI1; Spi17
Gene Symbols Serpini1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human Neuroserpin. Recombinant protein control fragment (Product #RP-101034).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5274
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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