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Neuroserpin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728065 Shop All Proteintech Group Inc Products
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50-172-8065 150 μL
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Catalog No. 50-172-8065 Supplier Proteintech Group Inc Supplier No. 125581AP150UL
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Rabbit Polyclonal Antibody

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a domitly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

Antigen Neuroserpin
Applications Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SERPINI1
Gene Accession No. O35684, Q99574, Q9JLD2
Gene Alias neuroserpin, Peptidase inhibitor 12, PI 12, PI12, Serpin I1, SERPINI1
Gene Symbols SERPINI1
Host Species Rabbit
Immunogen Neuroserpin Fusion Protein Ag3275
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116459, 20713, 5274
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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