Neuroserpin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 125581AP150UL

Catalog No. 50-172-8065

Description

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a domitly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: Neuroserpin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SERPINI1
• Gene Alias: neuroserpin, Peptidase inhibitor 12, PI 12, PI12, Serpin I1, SERPINI1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116459, 20713, 5274
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O35684, Q99574, Q9JLD2
• Gene Symbols: SERPINI1
• Immunogen: Neuroserpin Fusion Protein Ag3275
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG