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Neuroserpin Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981262
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100 μL
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50-198-1262 100 μL
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Catalog No. 50-198-1262 Supplier Bioss Supplier No. BS11317R
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Description

Rabbit Polyclonal Antibody

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

Antigen Neuroserpin
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Serpini1
Gene Accession No. Q99574
Gene Alias AI837402; DKFZp781N13156; Neuroserpin; Ns; Peptidase inhibitor 12; Pi12; PI-12; protease inhibitor 17; raPIT5a; serine (or cysteine) peptidase inhibitor, clade I, member 1; serine (or cysteine) proteinase inhibitor clade member 1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; Serine protease inhibitor 17; serpin family I member 1; Serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; serpin peptidase inhibitor, clade I, member 1; SERPINI1; Spi17
Gene Symbols Serpini1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Neuroserpin.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5274
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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