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Tocris Bioscience™ NF 023
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Catalog No. 124050
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12-405-0 50 mg
12-401-0 10 mg
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Catalog No. 12-405-0 Supplier Tocris Bioscience™ Supplier No. 1240/50
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Selective and competitive P2X1 antagonist

A subtype-selective, competitive and reversible P2X1 receptor antagonist. Displays IC50 values of 0.21, 28.9, > 50 and > 100 μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also selectively inhibits the α-subunit of Go/i (EC50 ∽300 nM). Also inhibits DNA-binding activity of HMGA2 (IC50 = 10.63 μM).

Chemical Identifiers

CAS 104869-31-0
Molecular Formula C35H20N4Na6O21S6

Specifications

Quantity 50 mg
Formula Weight 1162.86
Purity >98%
Molecular Weight (g/mol) 1162.851
Chemical Name or Material NF 023
Recommended Storage Desiccate at Room Temperature
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