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NF-H Antibody (RT-97 + NR-4), HRP, Novus Biologicals™
SDP

Catalog No. NB007104 Shop All R&D Systems Products
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NB007104 0.1 mL
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Catalog No. NB007104 Supplier Novus Biologicals Supplier No. NBP247664H
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Description

Mouse Monoclonal Antibody

NF-H Monoclonal specifically detects NF-H in Human, Mouse, Rat, Porcine, Chicken samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen NF-H
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone RT-97 + NR-4
Conjugate HRP
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation PBS with No Preservative
Gene Alias 200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Gene Symbols NEFH
Host Species Mouse
Immunogen Triton-X 100 insoluble proteins of rat brain (RT-97); Neurofilaments from porcine spinal cord (NR-4) (Uniprot: P12036)
Purification Method Protein G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Autophagy, Cell Biology, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience
Primary or Secondary Primary
Test Specificity This monoclonal antibody reacts with a 200kDa and 68kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Target Species Human, Mouse, Rat, Pig, Chicken
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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