Invitrogen™ NF-H Monoclonal Antibody (RNF 404)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ OMA106115

Catalog No. OMA106115

Description

OMA1-06115 specifically detects the phosphorylated 200 kDa neurofilament from Human, Bovine, Canine, Chicken, Guinea Pig, Non-human primate, mouse, Rabbit, Rat, Ovine and Xenopus tissues. OMA1-06115 has been successfully used in Western blot, IHC (F), and IHC (P) procedures. By Western blot, this antibody detects an ~200 kDa protein representing the phosphorylated form of the 200 kDa neurofilament from human brain homogenate. OMA1-06115 antigen is cytoskeletal preparation of calf brain tissue.

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

Specifications

• Antigen: NF-H
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P12036, P16884, P19246
• Gene Symbols: Nefh, nefh.L
• Immunogen: Neurofilament preparation of calf brain tissue.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Rabbit, Monkey, Bovine, Sheep, Chicken, Guinea Pig, Frog
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: RNF 404
• Conjugate: Unconjugated
• Gene: Nefh
• Gene Alias: 200 kDa neurofilament protein; CMT2CC; heavy neurofilament protein; I79_012512; intermediate filament protein; KIAA0845; LOW QUALITY PROTEIN: neurofilament heavy polypeptide; mKIAA0845; NEF3; Nefh; nefh.L; neurofilament; neurofilament 200kDa; neurofilament heavy; neurofilament heavy L homeolog; neurofilament heavy polypeptide; neurofilament heavy polypeptide-like; neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF200; Nfh; NF-H; NHC; XELAEV_18007418mg
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 100101753, 100357177, 100716406, 101107472, 108715402, 24587, 380684, 417020, 442940, 4744, 528842
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid