Invitrogen™ NF-H Monoclonal Antibody (RNF 405)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ OMA106117

Catalog No. OMA106117

Description

OMA1-06117 reacts exclusively with the phosphorylated form of the 200 kDa neurofilament from human, mouse, rat, canine, rabbit, monkey, bovine, ovine, hamster, chicken, guinea pig, and Xenopus laevis tissues. OMA1-06117 has been successfully used in Western blot and IHC (P) procedures. By Western blot, this antibody detects a single ~200 kDa protein representing phosphorylated neurofilament from rat brain homogenate. OMA1-06117 antigen is cytoskeletal preparation of calf brain tissue.

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

Specifications

• Antigen: NF-H
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P12036, P16884, P19246
• Gene Symbols: Nefh, nefh.L
• Immunogen: Neurofilament preparation of calf brain tissue.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Rabbit, Monkey, Bovine, Sheep, Hamster, Chicken, Guinea Pig, Frog, Zebrafish
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: RNF 405
• Conjugate: Unconjugated
• Gene: Nefh
• Gene Alias: 200 kDa neurofilament protein; CMT2CC; heavy neurofilament protein; I79_012512; intermediate filament protein; KIAA0845; LOW QUALITY PROTEIN: neurofilament heavy polypeptide; mKIAA0845; NEF3; Nefh; nefh.L; neurofilament; neurofilament 200kDa; neurofilament heavy; neurofilament heavy L homeolog; neurofilament heavy polypeptide; neurofilament heavy polypeptide-like; neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF200; Nfh; NF-H; NHC; XELAEV_18007418mg
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100101753, 100357177, 100716406, 100753127, 101107472, 101838568, 108715402, 24587, 380684, 417020, 442940, 4744, 528842
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid