NF-L Antibody (NFL/736), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2448930.2MG

Catalog No. NBP24489302

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence

NF-L Monoclonal antibody specifically detects NF-L in Human, Rat, Porcine, Chicken, Primate samples. It is validated for Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

• Antigen: NF-L
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml
• Gene Accession No.: P07196
• Gene Symbols: NEFL
• Immunogen: Recombinant human NEFL protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This MAb reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
• Content And Storage: Store at 4C.
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunofluorescence
• Clone: NFL/736
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: 68 kDa neurofilament protein, neurofilament protein, light chain, neurofilament subunit NF-L, Neurofilament triplet L protein, neurofilament, light polypeptide, neurofilament-light, NF68FLJ53642, NF-L, NFLlight polypeptide 68kDa
• Host Species: Mouse
• Molecular Weight of Antigen: 68 kDa
• Quantity: 0.2 mg
• Research Discipline: Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
• Gene ID (Entrez): 4747
• Target Species: Human, Rat, Pig, Chicken, Primate
• Form: Purified

For Research Use Only