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NF Mouse anti-Human, Clone: OTI3F7, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF190077

Encompass_Preferred

Catalog No. 50-165-9210


May include imposed supplier surcharges.
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Description

Description

Synthetic peptide sequence is EYQDLLNVKMALDIEIAAYRKLLEGEE Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Diseases associated with NEFM include Pineal Parenchymal Tumor Of Intermediate Differentiation and Wallerian Degeneration. Among its related pathways are Amyotrophic lateral sclerosis (ALS) and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include structural molecule activity and structural constituent of cytoskeleton.
Specifications

Specifications

NF
Monoclonal
Unconjugated
NEFL
RNA5-8N2
Mouse
Affinity Chromatography
RUO
4741, 4744, 4747
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI3F7
PBS with 8% trehalose and no preservative; pH 7.3
P07196, P07197, P12036
NEFH, NEFL, NEFM
Synthetic peptide corresponding to the conserved region of human neurofilament heavy polypeptide (NEFH), medium polypeptide (NEFM) and light polypeptide (NF68, NEFL)
100 μg
Primary
Human
Antibody
IgG1
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