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NF-YA Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc IHC00576T

Encompass_Preferred

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Catalog No. 50-157-2334


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla,

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Specifications

Specifications

NF-YA
Polyclonal
TBS with 0.1% BSA and 0.09% sodium azide
P23511, P23708
NFYA
Between 333 and 347
10 μL
Primary
Human, Mouse
Antibody
IgG
Immunohistochemistry
Unconjugated
NFYA
CAAT box DNA-binding protein subunit A, CAAT-box DNA binding protein subunit A, CBF-A, CBF-B, CCAAT-binding transcription factor subunit B, HAP2, HAP2 CCAAT-binding protein, NF-YA, nuclear transcription factor Y subunit A, nuclear transcription factor Y, alpha, Transcription factor NF-Y, A subunit
Rabbit
Antigen affinity chromatography
RUO
18044, 4800
4° C
Liquid
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