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NF-YA Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572334
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50-157-2334 10 μL
50-157-2333 100 μL
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Catalog No. 50-157-2334 Supplier Bethyl Laboratories, Inc Supplier No. IHC00576T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla,

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Specifications

Antigen NF-YA
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene NFYA
Gene Accession No. P23511, P23708
Gene Alias CAAT box DNA-binding protein subunit A, CAAT-box DNA binding protein subunit A, CBF-A, CBF-B, CCAAT-binding transcription factor subunit B, HAP2, HAP2 CCAAT-binding protein, NF-YA, nuclear transcription factor Y subunit A, nuclear transcription factor Y, alpha, Transcription factor NF-Y, A subunit
Gene Symbols NFYA
Host Species Rabbit
Immunogen Between 333 and 347
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18044, 4800
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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