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NF1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501556978
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20 μL; Unconjugated
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Catalog No.
50-155-6978 20 μL; Unconjugated
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Catalog No. 50-155-6978 Supplier Bethyl Laboratories, Inc Supplier No. A300140AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-Proteins like Ras. The NF1 gene is also classified as a tumor suppressor gene, and many studies have shown that mutations at the NF1 locus produce neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation and memory deficiency. Neurofibromin has also been associated with the intermediated filaments of the cytoskeleton. NF1 is expressed at its highest levels during periods of desmosome formation and mutations of NF1 produce variable cell sizes and morphologies.

Specifications

Antigen NF1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene NF1
Gene Accession No. P21359, Q04690
Gene Alias NF1, WSS, NFNS, VRNF
Gene Symbols NF1
Host Species Rabbit
Immunogen Between 2760 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18015, 4763
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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