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Invitrogen™ NF1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5145113
Description
Immunogen sequence: MARRDDLSFC QEMKFRNKMV EYLTDWVMGT SNQAADDDV Antigen sequence identity: Mouse 97%; Rat 100%.
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Specifications
NF1 | |
Polyclonal | |
Unconjugated | |
NF1 | |
AW494271; DKFZp686J1293; E030030H24Rik; FLJ21220; neurofibromatosis 1; Neurofibromatosis type 1; neurofibromatosis-related protein NF-1; Neurofibromin; neurofibromin 1; Neurofibromin truncated; NF1; Nf-1; NFNS; VRNF; WSS | |
Rabbit | |
Affinity chromatography | |
RUO | |
4763 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid | |
IgG |
Immunocytochemistry | |
0.3 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P21359 | |
NF1 | |
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 1023-1061. Recombinant protein control fragment (Product #RP-109759). | |
100 μL | |
Primary | |
Human | |
Antibody | |
Liquid |
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