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Invitrogen™ NF2 Polyclonal Antibody
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Catalog No. PIPA581227
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100 μL
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PIPA581227 100 μL
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Catalog No. PIPA581227 Supplier Invitrogen™ Supplier No. PA581227
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Description

Rabbit Polyclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Merlin/NF2.

NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. Merlin has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NF2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Nf2
Gene Accession No. P35240
Gene Alias ACN; BANF; Merlin; MGC123124; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromatosis 2; neurofibromin 2; neurofibromin 2 (bilateral acoustic neuroma); neurofibromin 2 (merlin); neurofibromin 2b (merlin); neurofibromin-2; Nf2; Nf-2; NF2a; nf2b; OTTHUMP00000199607; SCH; Schwannomerlin; schwannomin
Gene Symbols Nf2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to the center region of the human NF2.
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4771
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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