NF2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-1654	Bethyl Laboratories, Inc IHC00193T	10 μL
50-157-1653	Bethyl Laboratories, Inc IHC00193	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Gorilla, Chinese hamster and North

NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. Merlin has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predomit isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

Specifications

• Antigen: NF2
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: ACN, BANF, SCH
• Gene Symbols: NF2
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody

• Applications: Immunofluorescence, Immunohistochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P35240
• Gene ID (Entrez): 4771
• Immunogen: Between 550 and C-term
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: NF2