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Invitrogen™ NFATC1 Recombinant Rabbit Monoclonal Antibody (4I9P10)
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Catalog No. PIMA535314
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100 μL
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PIMA535314 100 μL
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Catalog No. PIMA535314 Supplier Invitrogen™ Supplier No. MA535314
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: PSSPSPPLPP ATQEPTCLQP CSPACPPATG RPQHLPSTVR RDESPTAGPR LLPEVHEDGS PNLAPIPVTV KREPEELDQL YLDDVNEIIR NDLSSTSTHS.

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFATC1
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 4I9P10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NFATC1
Gene Accession No. O95644
Gene Alias 2210017P03Rik; AI449492; AV076380; MGC138448; NFAT tra; NFAT trans; NFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NFATC1; NF-ATc1; NF-ATc1.2; Nfatcb; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; nuclear factor of activated T-cells 1; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NF-ATc
Gene Symbols NFATC1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 844-943 of human NFAT2 (O95644).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4772
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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