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Invitrogen™ NFATC1 Polyclonal Antibody
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Catalog No. PIPA5111680
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100 μL
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PIPA5111680 100 μL
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Catalog No. PIPA5111680 Supplier Invitrogen™ Supplier No. PA5111680
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GYGAALDGGP AGYFLSSGHT RPDGAPALES PRIEITSCLG LYHNNNQFFH DVEVEDVLPS SKRSPSTATL SLPSLEAYRD Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 84%.

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFATC1
Applications ChIP Assay, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NFATC1
Gene Accession No. O95644
Gene Alias 2210017P03Rik; AI449492; AV076380; MGC138448; NFAT tra; NFAT trans; NFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NFATC1; NF-ATc1; NF-ATc1.2; Nfatcb; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; nuclear factor of activated T-cells 1; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NF-ATc
Gene Symbols NFATC1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human NFATC1. Recombinant protein control fragment (Product #RP-105543).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4772
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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