Invitrogen™ NFATC1 Polyclonal Antibody

Catalog No.	Quantity
PA14196	100 μg

Catalog No. PA14196 Supplier Invitrogen™ Supplier No. PA14196

Description

Rabbit Polyclonal Antibody

PA1-4196 detects NFATc1 in human samples. NFATc1 is also known as NFAT2 or NFATc. PA1-4196 has been successfully used in Western blot procedures. The PA1-4196 immunogen is a synthetic peptide corresponding to residues S(211) P K T T D P E E G F P R(223) of human NFATc1.

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Specifications

• Antigen: NFATC1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% sodium azide
• Gene: NFATC1
• Gene Accession No.: O95644
• Gene Alias: 2210017P03Rik; AI449492; AV076380; MGC138448; NFAT tra; NFAT trans; NFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NFATC1; NF-ATc1; NF-ATc1.2; Nfatcb; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; nuclear factor of activated T-cells 1; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NF-ATc
• Gene Symbols: NFATC1
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to residues S(211) P K T T D P E E G F P R(223) of human NFATc1.
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4772
• Target Species: Human
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG