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Invitrogen™ NFATC2 Polyclonal Antibody
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Catalog No. PIPA582879
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100 μL
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Catalog No. Quantity
PIPA582879 100 μL
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Catalog No. PIPA582879 Supplier Invitrogen™ Supplier No. PA582879
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GSQPYYPQHP MVAESPSCLV ATMAPCQQFR TGLSSPDARY QQQNPAAVLY QRSKSLSPSL LGYQQPALMA APLSLADAHR SVLVHAGSQG QSSALLHPSP TNQQASPVIH YSPTN Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 84%.

The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFATC2
Applications ChIP Assay, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NFATC2
Gene Accession No. Q13469
Gene Alias AI607462; IB-IXL; KIAA0611; NFAT pre-existing s; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; Nfat1; NFAT1-D; Nfatc2; NF-ATc2; Nfatp; NF-ATp; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2; nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, preexisting component; OTTHUMP00000031291; preexisting nuclear factor of activated T-cells 2; T cell transcription factor NFAT1; T-cell transcription factor NFAT1
Gene Symbols NFATC2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NFATC2. Recombinant protein control fragment (Product #RP-89308).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4773
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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