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Invitrogen™ NFATC2 Polyclonal Antibody
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Catalog No. PIPA579732
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100 μg
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PIPA579732 100 μg
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Catalog No. PIPA579732 Supplier Invitrogen™ Supplier No. PA579732
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human K562 whole cell.

The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFATC2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene NFATC2
Gene Accession No. Q13469, Q60591
Gene Alias AI607462; IB-IXL; KIAA0611; NFAT pre-existing s; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; Nfat1; NFAT1-D; Nfatc2; NF-ATc2; Nfatp; NF-ATp; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2; nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, preexisting component; OTTHUMP00000031291; preexisting nuclear factor of activated T-cells 2; T cell transcription factor NFAT1; T-cell transcription factor NFAT1
Gene Symbols NFATC2
Host Species Rabbit
Immunogen E. coli-derived human NFAT1 recombinant protein (Position: Q594-H676).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18019, 311658, 4773
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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