Invitrogen™ NFATC2IP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565805

Catalog No. PIPA565805

Description

Immunogen sequence: SPWKTKLRTKD KEEKKKTEFL DLDNSPLSPP SPRTKSRTHT RALKKLSEVN KRLQDLRSCL SPKPPQGQEQ QGQEDEVVLV E Highest antigen sequence identity to the following orthologs - mouse 67%, rat 69%.

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.

Specifications

• Antigen: NFATC2IP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFATC2IP
• Gene Alias: 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; ESC2; NFATC2-interacting protein; NFATC2IP; NIP45; nuclear factor of activated T-cells 2 interacting protein; nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein; RAD60
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84901
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NCF5
• Gene Symbols: NFATC2IP
• Immunogen: Recombinant Human NFATC2IP. Recombinant protein control fragment (Product #RP-106479).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG