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Invitrogen™ NFATC2IP Polyclonal Antibody
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Catalog No. PIPA599664
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100 μL
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PIPA599664 100 μL
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Catalog No. PIPA599664 Supplier Invitrogen™ Supplier No. PA599664
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NFATc2IP.

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFATC2IP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NFATC2IP
Gene Accession No. Q8NCF5
Gene Alias 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; ESC2; NFATC2-interacting protein; NFATC2IP; NIP45; nuclear factor of activated T-cells 2 interacting protein; nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein; RAD60
Gene Symbols NFATC2IP
Host Species Rabbit
Immunogen A synthesized peptide derived from human NFATC2IP(Accession Q8NCF5), corresponding to amino acid residues A155-P205.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84901
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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