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Invitrogen™ NFE2 Polyclonal Antibody
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Catalog No. PIPA551659
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PIPA551659 100 μL
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Catalog No. PIPA551659 Supplier Invitrogen™ Supplier No. PA551659
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SRNRVIQLST SELGEMELTW QEIMSITELQ GLNAPSEPSF EPQAPAPYLG PPPPTTYCPC SIHPDSGFPL PPPPYELPAS TSHVPDPPYS YGNMAIPVSK PLSLSGLLSE PLQDPLALLD IGLPAGPPKP QEDPES Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFE2
Applications ChIP Assay, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NFE2
Gene Accession No. Q16621
Gene Alias leucine zipper protein NF-E2; NFE2; NF-E2; NF-E2/P45; nuclear factor (erythroid-derived 2), 45kD; nuclear factor (erythroid-derived 2), 45kDa; nuclear factor, erythroid 2; nuclear factor, erythroid derived 2; nuclear factor, erythroid-derived 2 45 kDa subunit; p45; p45 NF-E2; p45NFE2; p45nf-e2; Transcription factor NF-E2 45 kDa subunit
Gene Symbols NFE2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NFE2. Recombinant protein control fragment (Product #RP-100710).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4778
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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