Invitrogen™ NFE2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567842

Catalog No. PIPA567842

Description

Predicted to react with Mouse and Rat samples.

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Specifications

• Antigen: NFE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFE2
• Gene Alias: leucine zipper protein NF-E2; NFE2; NF-E2; NF-E2/P45; nuclear factor (erythroid-derived 2), 45kD; nuclear factor (erythroid-derived 2), 45kDa; nuclear factor, erythroid 2; nuclear factor, erythroid derived 2; nuclear factor, erythroid-derived 2 45 kDa subunit; p45; p45 NF-E2; p45NFE2; p45nf-e2; Transcription factor NF-E2 45 kDa subunit
• Host Species: Rabbit
• Purification Method: affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18022, 366998, 4778
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q07279, Q16621, Q6AYT2
• Gene Symbols: NFE2
• Immunogen: Synthesized peptide derived from human NFE2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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