NFE2L2 Mouse anti-Human, Clone: OTI8A10, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA805014

Catalog No. 50-168-0521

Description

Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription activator which plays a key role in protecting the cell from oxidative stress and inflammation. It is primarily localized in the cytoplasm under normal conditions, but under conditions of oxidative stress, Nrf2 migrates to the nucleus to upregulate expression of genes with ARE (antioxidant response elements) in the promoter region. The upregulated genes include those involved in cellular protection, drug transport, detoxification, and anti-oxidant defense. The protein is ubiquitously expressed in various tissues, with the highest levels found in kidney, muscle, lung, heart, liver, and brain.

Specifications

• Antigen: NFE2L2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q16236
• Gene Symbols: NFE2L2
• Immunogen: Human recombit protein fragment corresponding to amino acids 330-605 of human NFE2L2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI8A10
• Conjugate: Unconjugated
• Gene: NFE2L2
• Gene Alias: HEBP1, IMDDHH, NRF2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4780
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid